Studies on intravenous glucose tolerance curve. 4. Experiments on normal and adrenalectomized rats.

There are many works on change in the blood sugar values following the intravenous administration of glucose (Thaunhauser and Pfitzer,1913;Tunbridge and Allibone,1940;Samuels et al.,1937 a,b;Greville,1943;Soskin,1944;Nonobe,1952;Amatuzio,1953;Hirata,1954;Scow and Cornfield,1954 a,b).It is generally known that the pituitary,adrenocortical and thyroid hormones concerned with carbohydrate metabolism.At present, however,the effect of these hormones upon the glucose tolerance is not completely elucidated.Recently, Takeuchi et al.(1957)and Fukushima(1957 a,b) made experiments on this problem with dogs and rabbits,respectively,and reported that the so-called atypical